ANTI-CD3 ANTIBODIES, ACTIVATABLE ANTI-CD3 ANTIBODIES, MULTISPECIFIC ANTI-CD3 ANTIBODIES, MULTISPECIFIC ACTIVATABLE ANTI-CD3 ANTIBODIES, AND METHODS OF USING THE SAME

The invention relates generally to antibodies, activatable antibodies, multispecific antibodies, and multispecific activatable antibodies that specifically bind to at least CD3, as well as to methods of making and using these antibodies, activatable antibodies, multispecific antibodies, and/or multi...

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Main Authors SAGERT, JASON GARY, HOSTETTER, DANIEL ROBERT, WHITE, CLAYTON, RICHARDSON, JENNIFER HOPE, LA PORTE, SHERRY LYNN, RAZO, OLIVIA JENNIFER, IRVING, BRYAN ALLEN
Format Patent
LanguageEnglish
French
Published 17.03.2016
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention relates generally to antibodies, activatable antibodies, multispecific antibodies, and multispecific activatable antibodies that specifically bind to at least CD3, as well as to methods of making and using these antibodies, activatable antibodies, multispecific antibodies, and/or multispecific activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications. L'invention concerne de manière générale des anticorps, des anticorps activables, des anticorps multispécifiques et des anticorps activables multispécifiques qui se lient spécifiquement au moins à CD3, ainsi que des procédés de fabrication et d'utilisation de ces anticorps, anticorps activables, anticorps multispécifiques et/ou anticorps activables multispécifiques dans diverses indications thérapeutiques, diagnostiques et prophylactiques.
Bibliography:Application Number: WO2015US42053