COMPOSITIONS AND METHODS FOR SELECTIVELY DEPLETING SENESCENT CELLS

The present disclosure provides compositions and methods for selectively killing senescent cells, wherein the composition comprises piperlongumine (PL) or derivative thereof. The selective killing of senescent cells may delay aging and/or treat age-related disorders. La présente invention concerne d...

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Bibliographic Details
Main Authors SHAO, LIJIAN, FENG, WEI, LUO, YI, LIU, XINGUI, ZHOU, DAOHONG, WANG, YINGYING, ZHENG, GUANGRONG, CHANG, JIANHUI
Format Patent
LanguageEnglish
French
Published 28.01.2016
Subjects
AGRICULTURE
ANIMAL HUSBANDRY
BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
PEST REPELLANTS OR ATTRACTANTS
PLANT GROWTH REGULATORS
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF
TRAPPING
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Summary:The present disclosure provides compositions and methods for selectively killing senescent cells, wherein the composition comprises piperlongumine (PL) or derivative thereof. The selective killing of senescent cells may delay aging and/or treat age-related disorders. La présente invention concerne des compositions et des procédés pour tuer sélectivement des cellules sénescentes, la composition comprenant la piperlongumine (PL) ou un dérivé de celle-ci. La destruction sélective de cellules sénescentes permet de retarder le vieillissement et/ou traiter les troubles liés à l'âge.
Bibliography:Application Number: WO2015US41470