THERAPY OF CARDIOMYOPATHY BY INTRAMYOCARDIAL CELL DELIVERY AND CYTOKINE ADMINISTRATION

The present invention provides a composition comprising cells obtainable by bone marrow aspiration, or multipotent or pluripotent progenitor cells,and granulocyte-colony stimulating factor (G-CSF), as a combined preparation for simultaneous, separate or sequential use in the therapy of cardiomyopath...

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Bibliographic Details
Main Authors MARTIN, JOHN FRANCIS, MATHUR, ANTHONY
Format Patent
LanguageEnglish
French
Published 17.12.2015
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides a composition comprising cells obtainable by bone marrow aspiration, or multipotent or pluripotent progenitor cells,and granulocyte-colony stimulating factor (G-CSF), as a combined preparation for simultaneous, separate or sequential use in the therapy of cardiomyopathy in a subject, wherein the cells are administered directly to the myocardium of the subject. La présente invention concerne une composition comprenant des cellules pouvant être obtenues par aspiration de la moelle osseuse, ou des cellules progénitrices multipotentes ou pluripotentes, et le facteur de croissance hématopoïétique de la lignée granulocytaire (G-CSF), et se présentant sous la forme d'une préparation combinée aux fins d'utilisation simultanée, séparée ou séquentielle dans le traitement de la cardiomyopathie d'un patient, les cellules étant administrées directement dans le myocarde du patient.
Bibliography:Application Number: WO2015GB51714