PYRAZOLONE DERIVATIVES AS NITROXYL DONORS

The disclosed subject matter provides pyrazolone derivative compounds, pharmaceutical compositions comprising such compounds, kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such...

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Main Authors COURTNEY, STEPHEN, M, BROOKFIELD, FREDERICK, A, FROST, LISA, M, TOSCANO, JOHN, P, GUTHRIE, DARYL, A, KALISH, VINCENT, J, NORTH, CARL, L
Format Patent
LanguageEnglish
French
Published 03.12.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The disclosed subject matter provides pyrazolone derivative compounds, pharmaceutical compositions comprising such compounds, kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating heart failure. L'invention concerne des composés dérivés de pyrazolone, des compositions pharmaceutiques les comprenant et des kits comprenant ces composés, ainsi que des procédés d'utilisation de ces composés ou compositions pharmaceutiques. L'invention concerne en particulier des procédés d'utilisation de ces composés ou compositions pharmaceutiques pour traiter l'insuffisance cardiaque.
Bibliography:Application Number: WO2015US32496