ION CHANNEL MODULATORS AND USES THEREOF

• Main Authors: JONES, CLARE, LINLEY, JOHN, SNIJDER, HARM JAN, BUTTON, JAMES, GROVES, MARIA, SHIBATA, YOKO, WILLIAMS, WENDY A, SRIDHARAN, SUDHARSAN, HUANG, LING, DOBSON, CLAIRE
• Format: Patent
• Language: English; French
• Published: 05.11.2015
• Subjects: CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES

The invention provides antibodies that specifically bind a P2X4 polypeptide and modulate P2X4 channel activity, recombinant P2X4 polypeptides and methods for generating such polypeptides, as well as compositions and methods for generating anti-P2X4 antibodies, and methods of using P2X4 antibodies fo...