TRANS-ACTING ELEMENTS FOR INTRACELLULAR DELIVERY OF NUCLEIC ACID SEQUENCES

• Main Authors: JAIN, HARSH, V, BEAUCAGE, SERGE, L
• Format: Patent
• Language: English; French
• Published: 17.09.2015
• Subjects: CHEMISTRY; DERIVATIVES THEREOF; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SUGARS

The invention concerns compounds of the formula (Z)x wherein: each Z is independently selected from 2'-deoxythymidinyl moiety, 2'-deoxyadenosinyl moiety, and a 2'-deoxycytidinyl moiety, x is an integer from 5 - 20, wherein said 2'-deoxythymidinyl moieties are connected by thiopho...