PYRAZOLE AMIDE DERIVATIVE

• Main Authors: CEE, VICTOR J, KAKUDA, SHINJI, BOOKER, SHON KEITH, BREGMAN, HOWARD, CHAKKA, NAGASREE, SHIMADA, KEIKO, OLSON, STEVEN H, HUA, ZIHAO, PENNINGTON, LEWIS D, BECK, HILARY PLAKE, HIRATA, JUN, WHITE, RYAN D, WURZ, RYAN P, FOX, BRIAN M, HIBIYA, KENTA, OKADA, KAZUHISA, YI, SHUYAN, OONO, HIROYUKI, SASAKI, KOSUKE, LOPEZ, PATRICIA, NAKAJIMA, RYOTA, CUSHING, TIMOTHY D, HAO, XIAOLIN, SHIN, YOUNGSOOK, GEUNS-MEYER, STEPHANIE, HUMAN, JASON, ZHENG, XIAO MEI, EPSTEIN, OLEG
• Format: Patent
• Language: English; French
• Published: 03.09.2015
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to a novel compound having a function of inhibiting RORγ activity. The present invention also relates to pharmaceutical composition comprising the compound, a use of the compound in treating or preventing autoimmune diseases, inflammatory diseases, metabolic diseases, or cancer diseases. La présente invention concerne un nouveau composé ayant une fonction d'inhibition de l'activité RORγ. La présente invention concerne également une composition pharmaceutique comprenant le composé, une utilisation du composé dans le traitement ou la prévention de maladies auto-immunes, de maladies inflammatoires, de maladies métaboliques, ou de maladies cancéreuses.