LYOPHILIZED FORMULATION OF TREOSULFAN
The present invention relates to an improved solid formulation of (2S,3S)-2,3-Dihydroxy-4- methylsulfonyloxybutyl] methanesulfonate. The improved formulations are lyophilized pharmaceutical solid composition containing treosulfan for reconstitution with water to provide a solution for parenteral adm...
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Main Authors | , , , , , |
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Format | Patent |
Language | English French |
Published |
23.07.2015
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to an improved solid formulation of (2S,3S)-2,3-Dihydroxy-4- methylsulfonyloxybutyl] methanesulfonate. The improved formulations are lyophilized pharmaceutical solid composition containing treosulfan for reconstitution with water to provide a solution for parenteral administration. The present invention also relates to Polymorphic Form I and II of treosulfan.
La présente invention concerne une formulation solide améliorée de (2S,3S)-2,3-dihydroxy -4-méthylsulfonyloxybutyl]méthanesulfonate. Ces formulations améliorées sont constituées d'une composition pharmaceutique solide lyophilisée contenant du tréosulfan à reconstituer avec de l'eau pour obtenir une solution pour une administration parentérale. La présente invention concerne également les formes polymorphes I et II du tréosulfan. |
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Bibliography: | Application Number: WO2014IN00692 |