NOVEL COMPOUNDS HAVING A TETRACYCLIC IRIDOID SKELETON AND AN ANTI-TRYPANOSOMAL, ANTI-LEISHMANIAL AND ANTI-PLASMODIAL AGENTS COMPRISING THE SAME AS AN ACTIVE INGREDIENT

• Main Authors: OKINE, LAUD KENNETH NII-AYITEY, UTO, TAKUHIRO, YAMAOKA, SHOJI, SUZUKI, MITSUKO, APPIAH-OPONG, REGINA, OHTA, NOBUO, MORINAGA, OSAMU, ABOAGYE, FREDERICK ASARE, AYI, IRENE, EDOH, DOMINIC ADOTEI, BOSOMPEM, KWABENA MANTE, SHOYAMA, YUKIHIRO, BOAKYE, DANIEL ADJEI, NYARKO, ALEXANDER KWADWO, KORAM, KWADWO ANSAH, TUNG, NGUYEN HUU
• Format: Patent
• Language: English; French
• Published: 16.07.2015
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention provides anti-trypanosomal, anti-leishmanial or anti-plastmodial agent for treating, preventing trypanosomiasis, leishmaniasis or malaria, respectively, of mammals, which comprises a compound having the tetracyclic iridoid skeleton represented by a general formula (I). La présente invention concerne des agents anti-Trypanosoma, ant-Leishamnia ou anti-Plasmodium permettant de traiter et de prévenir, respectivement, la trypasonomiase, la leishmaniose ou le paludisme, chez les mammifères et comprenant un composé comportant la chaîne principale iridoïde tétracyclique représentée par la formule générale (I).