ANTIBODIES DIRECTED AGAINST THE LUKGH (LUKAB) TOXIN OF STAPHYLOCOCCUS AUREUS AND ANTIBODY SEQUENCES
The invention provides for an antibody comprising at least one binding site that specifically binds to a LukGH complex, which antibody comprises at least an antibody heavy chain variable region (VH), which comprises any of the CDR1 to CDR3 sequences as listed in Table 1, or functionally active CDR v...
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| Main Authors | , , , , , , , |
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| Format | Patent |
| Language | English French |
| Published |
25.06.2015
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The invention provides for an antibody comprising at least one binding site that specifically binds to a LukGH complex, which antibody comprises at least an antibody heavy chain variable region (VH), which comprises any of the CDR1 to CDR3 sequences as listed in Table 1, or functionally active CDR variants thereof.
La présente invention concerne un anticorps comprenant au moins un site de liaison qui se lie, de façon spécifique, à un complexe LukGH, ledit anticorps comprenant au moins une région variable de chaîne lourde d'anticorps (VH), comportant l'une quelconque des séquences CDR1 à CDR3, énumérées dans le tableau 1, ou des variants CDR fonctionnellement actifs de ces séquences. |
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| AbstractList | The invention provides for an antibody comprising at least one binding site that specifically binds to a LukGH complex, which antibody comprises at least an antibody heavy chain variable region (VH), which comprises any of the CDR1 to CDR3 sequences as listed in Table 1, or functionally active CDR variants thereof.
La présente invention concerne un anticorps comprenant au moins un site de liaison qui se lie, de façon spécifique, à un complexe LukGH, ledit anticorps comprenant au moins une région variable de chaîne lourde d'anticorps (VH), comportant l'une quelconque des séquences CDR1 à CDR3, énumérées dans le tableau 1, ou des variants CDR fonctionnellement actifs de ces séquences. |
| Author | MIRKINA, IRINA BATTLES, MICHAEL BENJAMIN ROUHA, HARALD NIELSON, NELS TUSHAR, S. JAIN BADARAU, ADRIANA WALKER, LAURA M NAGY, ESZTER |
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| DocumentTitleAlternate | ANTICORPS DIRIGÉS CONTRE LA TOXINE LUKGH (LUKAB) DU STAPHYLOCOQUE DORÉ ET SÉQUENCES D'ANTICORPS |
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| Notes | Application Number: WO2014EP78708 |
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| Snippet | The invention provides for an antibody comprising at least one binding site that specifically binds to a LukGH complex, which antibody comprises at least an... |
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| SubjectTerms | CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES |
| Title | ANTIBODIES DIRECTED AGAINST THE LUKGH (LUKAB) TOXIN OF STAPHYLOCOCCUS AUREUS AND ANTIBODY SEQUENCES |
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