ANTIBODIES DIRECTED AGAINST THE LUKGH (LUKAB) TOXIN OF STAPHYLOCOCCUS AUREUS AND ANTIBODY SEQUENCES

The invention provides for an antibody comprising at least one binding site that specifically binds to a LukGH complex, which antibody comprises at least an antibody heavy chain variable region (VH), which comprises any of the CDR1 to CDR3 sequences as listed in Table 1, or functionally active CDR v...

Full description

Saved in:
Bibliographic Details
Main Authors MIRKINA, IRINA, ROUHA, HARALD, BADARAU, ADRIANA, BATTLES, MICHAEL BENJAMIN, NAGY, ESZTER, NIELSON, NELS, WALKER, LAURA M, TUSHAR, S. JAIN
Format Patent
LanguageEnglish
French
Published 25.06.2015
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
Online AccessGet full text

Cover

More Information
Summary:The invention provides for an antibody comprising at least one binding site that specifically binds to a LukGH complex, which antibody comprises at least an antibody heavy chain variable region (VH), which comprises any of the CDR1 to CDR3 sequences as listed in Table 1, or functionally active CDR variants thereof. La présente invention concerne un anticorps comprenant au moins un site de liaison qui se lie, de façon spécifique, à un complexe LukGH, ledit anticorps comprenant au moins une région variable de chaîne lourde d'anticorps (VH), comportant l'une quelconque des séquences CDR1 à CDR3, énumérées dans le tableau 1, ou des variants CDR fonctionnellement actifs de ces séquences.
Bibliography:Application Number: WO2014EP78708