PROCESS FOR PREPARATION OF CRYSTALLINE FORM I OF LINEZOLID AND ITS COMPOSITIONS

The present invention relates to a process for the preparation of crystalline form I of linezolid, comprising providing a solution of linezolid in a solvent, crystallizing and recovering the solid of Linezolid in crystalline form I at elevated temperature. The present invention also relates to the u...

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Main Authors DAVE, AXAYKUMAR, JARSANIA, SAMIR, TIWARI, KARUNESH KUMAR, CHAUHAN, YOGENDARKUMAR, TAMBE, VIJAY, GHORPADE, PRAVIN POPATRAO
Format Patent
LanguageEnglish
French
Published 14.05.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to a process for the preparation of crystalline form I of linezolid, comprising providing a solution of linezolid in a solvent, crystallizing and recovering the solid of Linezolid in crystalline form I at elevated temperature. The present invention also relates to the use of crystalline form I of linezolid prepared by the method of the present invention for preparing pharmaceutical compositions. La présente invention concerne un procédé pour la préparation de la forme cristalline I de linézolide, comprenant la fourniture d'une solution de linézolide dans un solvant, la cristallisation et la récupération du solide de linézolide sous forme cristalline I à température élevée. La présente invention concerne également l'utilisation de la forme cristalline I de linézolide préparée par le procédé de la présente invention pour la préparation de compositions pharmaceutiques.
Bibliography:Application Number: WO2014IB65837