GLUCOPYRANOSYL DERIVATIVES AND THEIR USES IN MEDICINE

Disclosed are glucopyranosyl derivatives used as sodium dependent glucose cotransporters (SGLTs) inhibitors, intermediates or preparation processes thereof, and pharmaceutical uses thereof, especially glucopyranosyl derivatives represented by Formula (I), or pharmaceutically acceptable salts or all...

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Main Authors YUAN, MINGYUN, TANG, PENGCHO, WU, WUYONG, WEN, JIAPING, GU, ZHENG, LU, YONGHUA, ZHU, GUOZHI, WANG, YINCAI, WANG, HERAN, ZHANG, ZONGYUAN, CHEN, GANG, KANG, PANPAN, WEI, YONGGANG
Format Patent
LanguageEnglish
French
Published 02.04.2015
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Summary:Disclosed are glucopyranosyl derivatives used as sodium dependent glucose cotransporters (SGLTs) inhibitors, intermediates or preparation processes thereof, and pharmaceutical uses thereof, especially glucopyranosyl derivatives represented by Formula (I), or pharmaceutically acceptable salts or all stereoisomers thereof, pharmaceutical compositions containing these derivatives and their uses for treatment of diabetes and diabetes-related diseases. La présente invention concerne des dérivés de glucopyranosyl utilisés comme inhibiteurs des co-transporteurs du glucose dépendants du sodium (SGLT), des intermédiaires ou des procédés de préparation et des utilisations pharmaceutiques de ceux-ci, en particulier des dérivés de glucopyranosyl représentés par la formule (I), ou des sels pharmaceutiquement acceptables de ceux-ci, ou tous les stéréoisomères de ceux-ci, une composition pharmaceutique contenant ces dérivés et leurs utilisations pour le traitement du diabète et de maladies associées au diabète.
Bibliography:Application Number: WO2014CN87587