BENZIMIDAZOLE CARBOXYLIC ACID DERIVATIVES, COMPOSITIONS, AND METHODS OF USE AS AURORA KINASE INHIBITORS

The invention provides benzimidazole carboxylic acid derivatives that inhibit Aurora kinase, pharmaceutical compositions comprising compounds that inhibit Aurora kinase, and methods of treatment using the compounds of the present invention or pharmaceutical compositions comprising compounds of the p...

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Bibliographic Details
Main Authors BANNER, WILLIAM KENNETH, DAVIS, STEPHEN THOMAS, KALPATHY, SANTHOSH, POLISETTI, DHARMA RAO, ANDREWS, ROBERT CARL, BONDLELA, MURALIDHAR
Format Patent
LanguageEnglish
French
Published 19.03.2015
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention provides benzimidazole carboxylic acid derivatives that inhibit Aurora kinase, pharmaceutical compositions comprising compounds that inhibit Aurora kinase, and methods of treatment using the compounds of the present invention or pharmaceutical compositions comprising compounds of the present invention. L'invention concerne des dérivés d'acide benzimidazole-carboxylique qui inhibent la kinase Aurora, des compositions pharmaceutiques comprenant des composés qui inhibent la kinase Aurora et des procédés de traitement utilisant les composés de la présente invention ou des compositions pharmaceutiques comprenant des composés de la présente invention.
Bibliography:Application Number: WO2014US38737