METHODS FOR MODULATING RNA ALTERNATIVE SPLICING IN A SUBJECT IN NEED THEREOF

The present invention relates to methods for modulating RNA alternative splicing in a subject. In particular, the present invention relates to a method for modulating RNA alternative splicing in a subject in need thereof comprising administering the subject with a therapeutically amount of an inhibi...

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Bibliographic Details
Main Authors LAUSTRIAT, DELPHINE, BAGHDOYAN, SANDRINE, MARTINAT, CÉCILE, PESCHANSKI, MARC, NISSAN, XAVIER
Format Patent
LanguageEnglish
French
Published 16.10.2014
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to methods for modulating RNA alternative splicing in a subject. In particular, the present invention relates to a method for modulating RNA alternative splicing in a subject in need thereof comprising administering the subject with a therapeutically amount of an inhibitor of mitochondrial complex I activity. La présente invention concerne des procédés pour la modulation de l'épissage alternatif de l'ARN chez un sujet. En particulier, la présente invention concerne un procédé pour la modulation de l'épissage alternatif de l'ARN chez un sujet en ayant besoin, comprenant l'administration au sujet par une quantité thérapeutiquement efficace d'un inhibiteur de l'activité du complexe I mitochondrial.
Bibliography:Application Number: WO2014EP57321