ANTIBODIES AND METHODS OF DETECTION

Disclosed herein are methods for detecting surface expressed proteins, for example, B7 family members such as PD-L1. Also disclosed are antibodies and antibody fragments that specifically bind PD-L1 and methods for generating antibodies and antibody fragments that specifically bind PD-L1. Cette inve...

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Bibliographic Details
Main Authors BROWN II, CHARLES, ROBERT, ROBBINS, PAUL, BRIAN, LEWIS, ARTHUR, RICHARD, LAVALLEE, THERESA, MARIE, REBELATTO, MARLON, CEZAR, AUSTIN, MARK, JULIAN
Format Patent
LanguageEnglish
French
Published 09.10.2014
Subjects
CHEMISTRY
COMBINATORIAL CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
TESTING
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Summary:Disclosed herein are methods for detecting surface expressed proteins, for example, B7 family members such as PD-L1. Also disclosed are antibodies and antibody fragments that specifically bind PD-L1 and methods for generating antibodies and antibody fragments that specifically bind PD-L1. Cette invention concerne des procédés de détection de protéines exprimées à la surface, par exemple, des membres de la famille B7 tels que PD-L1. Des anticorps et des fragments d'anticorps qui se lient spécifiquement à PD-L1 et des procédés de génération d'anticorps et de fragments d'anticorps qui se lient spécifiquement à PD-L1 sont en outre décrits.
Bibliography:Application Number: WO2014US24331