PYRROLOPYRIMINDINE CDK9 KINASE INHIBITORS

Disclosed are compound of Formula (Ia), wherein R1, R2, and R3 are as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds may be used as agents in the treatment of diseases, including cancer. Also provided are pharmaceutical compositions, comprising one or more...

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Bibliographic Details
Main Authors FLORJANCIC, ALAN S, GOSWAMI, RAJEEV, TONG, YUNSONG, SOUERS, ANDREW J, PENNING, THOMAS
Format Patent
LanguageEnglish
French
Published 02.10.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Disclosed are compound of Formula (Ia), wherein R1, R2, and R3 are as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds may be used as agents in the treatment of diseases, including cancer. Also provided are pharmaceutical compositions, comprising one or more compounds of Formula (Ia). L'invention concerne un composé de Formule (Ia), où R1, R2 et R3 sont tels que définis dans la description, et des sels pharmaceutiquement acceptables de celui-ci. Les composés peuvent être utilisés en tant qu'agents dans le traitement de maladies, comprenant le cancer. L'invention concerne également des compositions pharmaceutiques comprenant un ou plusieurs composés de Formule (Ia).
Bibliography:Application Number: WO2014US25670