TETHERING OF COFACTORS ON GRAPHENE-LIKE MATERIALS

• Main Authors: NARVAEZ VILLARRUBIA, CLAUDIA, W, ATANASSOV, PLAMEN, B, GARCIA, SERGIO, OMAR
• Format: Patent
• Language: English; French
• Published: 18.09.2014
• Subjects: BASIC ELECTRIC ELEMENTS; BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; COMPOUNDS THEREOF; CULTURE MEDIA; DERIVATIVES THEREOF; ELECTRICITY; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; INORGANIC CHEMISTRY; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; NON-METALLIC ELEMENTS; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PROCESSES OR MEANS, e.g. BATTERIES, FOR THE DIRECT CONVERSIONOF CHEMICAL INTO ELECTRICAL ENERGY; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGYGENERATION, TRANSMISSION OR DISTRIBUTION; SPIRITS; SUGARS; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE; VINEGAR; WINE

A family of customizable tethering molecules for tethering cofactors such as, but not necessarily limited to, nicotinamine adenine dinucleotide (NAD+/NADH, NAD(P)+/NAD(P)H) to substrates or structures formed from or including graphene-like materials is described. The tethered cofactor can then be used, for example, as biosensors employed for clinical diagnostic, food industry, medical drug development and environmental and military applications, as well as in reagentless biofuel cells for power generation. La présente invention concerne une famille de molécules de liaison personnalisables de liaison de cofacteurs, tels que, sans s'y limiter, un dinucléotide de nicotinamine adénine (NAD+/NADH, NAD(P)+/NAD(P)H), à des substrats ou des structures formés à partir de matériaux de type graphène ou les comprenant. Le cofacteur lié peut ensuite être utilisé, par exemple, en tant que biocapteur employé pour un diagnostic clinique, l'industrie alimentaire, le développement de médicaments et des applications environnementales et militaires, de même que pour des piles à biocombustible sans réactif de production d'énergie.