METHOD FOR PRODUCING BIOPOLYMER NANOPARTICLES CONTAINING OIL AND EXTRACTS OF AZADIRACHTA INDICA A. JUSS (NEEM), POWDERED BIOPOLYMER NANOPARTICLES AND MICROPARTICLES

• Main Authors: VIEIRA, PAULO CESAR, FORIM, MOACIR ROSSI, FERNANDES, JOÃO BATISTA, FERNANDES DA SILVA, MARIA FÁTIMA DAS GRAÇAS
• Format: Patent
• Language: English; French; Portuguese
• Published: 31.07.2014
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; TRAPPING

A method is described for producing biopolymer nanoparticles containing oil and extracts of Azadirachta indica A. Juss (Neem), the method comprising, in phase I, the preparation (10) of an aqueous emulsion of Neem oil and extracts, in phase II, the preparation (20) of a solution of biopolymer in an organic solvent, phases I and II being then mixed, and in phase III, the preparation (30) of an aqueous surfactant emulsion and the admixture of phase III to the mixture of phases I and II, producing a nanoparticle suspension that is stabilised. Also described are the resulting powdered biopolymer nanoparticles and microparticles. L'invention concerne un procédé d'obtention de nanoparticules biopolymères contenant de l'huile et des extraits d'Azadirachta indica A. Juss (Neem), comprenant, dans la phase I, la préparation (10) d'une émulsion aqueuse de l'huile et des extraits de Neem, dans la phase II, la préparation (20) d'une solution de biopolymère en solvant organique, les deux phases I et II étant ensuite mélangées, et dans la phase III, la préparation (30) d'une émulsion aqueuse d'un tensioactif et l'addition de celle-ci au mélange des phases I et II, d'où l'obtention d'une suspension de nanoparticules qui est stabilisée. L'invention concerne également les nanoparticules biopolymères et les microparticules en poudre obtenues. É descrito um processo de obtenção de nanopartículas biopoliméricas contendo óleo e extratos de Azadirachta Indica A. Juss (Neem) que compreende na Fase I, em (10), o preparo de uma emulsão aquosa do óleo e extratos de Neem, na Fase II, em (20), o preparo de uma solução de biopolímero em solvente orgânico, seguido da mistura das duas Fases I e II, e na Fase III, em (30), o preparo de uma emulsão aquosa de um tensoativo e adição da mesma à mistura das Fases I e II, obtendo uma suspensão de nanopartículas que é estabilizada. São também descritas as nanopartículas biopoliméricas e as micropartículas em pó obtidas.