ANTI-FGFR2 ANTIBODIES

Monoclonal antibodies that bind and inhibit biological activities of human FGFR2 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation or over-expression of FGFR2. L'invention concerne des anti...

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Main Authors ISMAIL, NESREEN, WEILER, SOLLY, MAZSA, ELIZABETH, WENG, ZHIGANG, MEETZE, KRISTAN, POLING, LAURA, WINSTON, WILLIAM, J, HASERLAT, SARA, TISSIRE, HAMID, GYURIS, JENO, BAI, AILIN, CHEN, TING
Format Patent
LanguageEnglish
French
Published 12.06.2014
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Monoclonal antibodies that bind and inhibit biological activities of human FGFR2 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation or over-expression of FGFR2. L'invention concerne des anticorps monoclonaux qui se lient et inhibent des activités biologiques de FGFR2 humain. Les anticorps peuvent être utilisés pour traiter des maladies et des troubles de prolifération cellulaire, comprenant certaines formes de cancer, associés à l'activation ou la surexpression de FGFR2.
Bibliography:Application Number: WO2013US73090