QUINUCLIDINE AMIDE DERIVATIVE AND MEDICINAL USE OF SAME

The purpose of the present invention is to provide a novel compound having a potent central nicotinic acetylcholine receptor-activating action and an antipruritic that exerts a beneficial effect on pruritus by a novel mechanism of action. The present invention provides a quinuclidine amide derivativ...

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Bibliographic Details
Main Authors AOKI, TAKUMI, HAYASHI, KENICHI, YAMAMOTO, MASASHI, UDAGAWA, SHUJI, OOSUMI, KAZUYA
Format Patent
LanguageEnglish
French
Japanese
Published 08.05.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The purpose of the present invention is to provide a novel compound having a potent central nicotinic acetylcholine receptor-activating action and an antipruritic that exerts a beneficial effect on pruritus by a novel mechanism of action. The present invention provides a quinuclidine amide derivative represented by the formula, or a pharmaceutically acceptable salt thereof. La présente invention concerne un nouveau composé présentant une action puissante d'activation du récepteur nicotinique d'acétylcholine central et un antipruritique qui exerce un effet bénéfique sur le prurit par un nouveau mécanisme d'action. La présente invention concerne un dérivé d'amide de quinuclidine représenté par la formule ou un sel pharmaceutiquement acceptable de celui-ci.
Bibliography:Application Number: WO2013JP79497