COMPOSITIONS AND METHODS FOR DETECTING SESSILE SERRATED ADENOMAS/POLYPS

• Main Authors: BURT, RANDALL, DELKER, DON, HAGEDORN, CURT
• Format: Patent
• Language: English; French
• Published: 24.04.2014
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; TESTING; VINEGAR; WINE

Provided are methods of predicting the likelihood that a colorectal polyp in a subject will develop into colorectal cancer. Further provided are methods of increasing the likelihood of detecting colorectal cancer at an early stage, the methods including predicting the likelihood that a colorectal polyp in a subject will develop into colorectal cancer, and when there is an increased likelihood that the colorectal polyp will develop into colorectal cancer, the frequency of colonoscopies administered to the subject are increased. Further provided are kits for predicting the likelihood that a colorectal polyp in a subject will develop into colorectal cancer. L'invention concerne des procédés de prédiction de la probabilité qu'un polype colorectal chez un sujet se développera en un cancer colorectal. L'invention concerne en outre des procédés d'augmentation de la probabilité de détection d'un cancer colorectal à un stade précoce, les procédés comprenant la prédiction de la probabilité qu'un polype colorectal chez un sujet se développera en un cancer colorectal et, lorsqu'il y a une plus grande probabilité que le polype colorectal se développera en cancer colorectal, la fréquence de colonoscopies administrées au sujet est augmentée. L'invention concerne en outre des nécessaires pour la prédiction de la probabilité qu'un polype colorectal chez un sujet se développera en un cancer colorectal.