RHODOBACTER FOR PREPARING TERPENOIDS

The invention relates to a Rhodobacter host cell, comprising a nucleic acid encoding - enzymes of a mevalonate pathway for making isoprenyl pyrophosphate (IPP) and its isomer dimethylallyl pyrophosphate (DMAPP); - an enzyme having catalytic activity for the condensation of IPP and DMAPP into geranyl...

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Bibliographic Details
Main Authors HUEMBELIN, MARKUS, KIERKELS, JOANNES GERARDUS THEODORUS, BEEKWILDER, MATRINUS JULIUS
Format Patent
LanguageEnglish
French
Published 23.01.2014
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The invention relates to a Rhodobacter host cell, comprising a nucleic acid encoding - enzymes of a mevalonate pathway for making isoprenyl pyrophosphate (IPP) and its isomer dimethylallyl pyrophosphate (DMAPP); - an enzyme having catalytic activity for the condensation of IPP and DMAPP into geranyl diphosphate (GPP) and - an enzyme having monoterpene synthase activity in the conversion of GPP into a monoterpene or sesquiterpene synthase activity. L'invention concerne une cellule hôte de Rhodobacter qui comporte un acide nucléique codant pour - des enzymes d'une voie de mévalonate pour fabriquer du pyrophosphate d'isoprényle (IPP) et son isomère pyrophosphate de diméthylallyle (DMAPP) ; - une enzyme ayant une activité catalytique pour la condensation d'IPP et de DMAPP en diphosphate de géranyle (GPP) et - une enzyme ayant une activité monoterpène synthase dans la conversion de GPP en une activité monoterpène ou sesquiterpène synthase.
Bibliography:Application Number: WO2013NL00040