4-(2-(6-SUBSTITUTED-HEXYLIDENE) HYDRAZINYL)BENZONITRILE AND PREPARATION THEREOF

The present teachings provide a compound of Formula (I-B): wherein R1-R10 are as described herein; a pharmaceutically acceptable salt of the compound, a geometric isomer of the compound, or a pharmaceutically acceptable salt of the geometric isomer. Also described are methods of preparing the same,...

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Bibliographic Details
Main Author RONSHEIM, MATTHEW
Format Patent
LanguageEnglish
French
Published 10.04.2014
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present teachings provide a compound of Formula (I-B): wherein R1-R10 are as described herein; a pharmaceutically acceptable salt of the compound, a geometric isomer of the compound, or a pharmaceutically acceptable salt of the geometric isomer. Also described are methods of preparing the same, as well as methods for preparing vilazodone using the same. La présente invention concerne un composé de formule (I-B) : dans laquelle R1 à R10 sont tels que présentement décrits ; un sel pharmaceutiquement acceptable du composé, un isomère géométrique du composé, ou un sel pharmaceutiquement acceptable de l'isomère géométrique. La présente invention concerne en outre des procédés de préparation de celui-ci, ainsi que des procédés pour préparer la vilazodone en utilisant celui-ci.
Bibliography:Application Number: WO2013US48858