METHODS, COMPOSITIONS AND KITS FOR THE DIAGNOSIS, PROGNOSIS AND MONITORING OF CANCER

• Main Authors: KEYS, DAVID, LAZAR, VLADIMIR, CHEN, CAIFU, LACROIX, LUDOVIC
• Format: Patent
• Language: English; French
• Published: 03.01.2014
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; TESTING; VINEGAR; WINE

Disclosed herein are methods for the diagnosis, prognosis and/or continuous monitoring of cancer and/or tumor progression in a subject. More specifically, the present invention relates to methods for detecting and/or quantifying tumoral-associated nucleic acids in a biological sample using a panel of cancer-specific markers, independent of cancer type, for the molecular detection of a broad range of cancer types for diagnostic, prognostic and therapeutic purposes. La présente invention concerne des procédés pour le diagnostic, le pronostic et/ou la surveillance continue d'un cancer et/ou d'une progression tumorale chez un patient. Plus spécifiquement, la présente invention concerne des procédés permettant de détecter et/ou de déterminer quantitativement des acides nucléiques associés aux tumeurs dans un échantillon biologique à l'aide d'un panel de marqueurs spécifique du cancer, indépendamment du type de cancer, pour la détection moléculaire d'une large plage de types de cancer à des fins diagnostiques, pronostiques et thérapeutiques.