GLUFOSFAMIDE COMBINATION THERAPIES FOR CANCER
The invention provides compositions and methods for treating cancer with glufosfamide in combination with an inhibitor of sodium-glucose transporter type 2 (SGLT2) to block the uptake of glucose in the proximal tubules of the kidneys to decrease renal toxicity. The invention relates to the fields of...
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| Main Authors | , , |
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| Format | Patent |
| Language | English French |
| Published |
24.10.2013
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The invention provides compositions and methods for treating cancer with glufosfamide in combination with an inhibitor of sodium-glucose transporter type 2 (SGLT2) to block the uptake of glucose in the proximal tubules of the kidneys to decrease renal toxicity. The invention relates to the fields of biomedicine, pharmacology, and molecular biology.
L'invention concerne des compositions et des méthodes de traitement du cancer par du glufosfamide en combinaison avec un inhibiteur du transporteur de sodium-glucose de type 2 (SGLT2) afin de bloquer la capture du glucose dans les tubules proximaux des reins, pour diminuer la toxicité rénale. L'invention concerne les domaines de la biomédecine, de la pharmacologie et de la biologie moléculaire. |
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| AbstractList | The invention provides compositions and methods for treating cancer with glufosfamide in combination with an inhibitor of sodium-glucose transporter type 2 (SGLT2) to block the uptake of glucose in the proximal tubules of the kidneys to decrease renal toxicity. The invention relates to the fields of biomedicine, pharmacology, and molecular biology.
L'invention concerne des compositions et des méthodes de traitement du cancer par du glufosfamide en combinaison avec un inhibiteur du transporteur de sodium-glucose de type 2 (SGLT2) afin de bloquer la capture du glucose dans les tubules proximaux des reins, pour diminuer la toxicité rénale. L'invention concerne les domaines de la biomédecine, de la pharmacologie et de la biologie moléculaire. |
| Author | THOMAS, EDWIN, J ANTHONY, FORREST, H PARRIS, MATTHEW |
| Author_xml | – fullname: PARRIS, MATTHEW – fullname: ANTHONY, FORREST, H – fullname: THOMAS, EDWIN, J |
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| Discipline | Medicine Chemistry Sciences Forestry Agriculture |
| DocumentTitleAlternate | POLYTHÉRAPIES PAR GLUFOSFAMIDE POUR LE CANCER |
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| Notes | Application Number: WO2012US53275 |
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| PublicationYear | 2013 |
| RelatedCompanies | THOMAS, EDWIN, J ANTHONY, FORREST, H PARRIS, MATTHEW ELEISON PHARMACEUTICALS LLC |
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| Snippet | The invention provides compositions and methods for treating cancer with glufosfamide in combination with an inhibitor of sodium-glucose transporter type 2... |
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| SubjectTerms | AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF TRAPPING |
| Title | GLUFOSFAMIDE COMBINATION THERAPIES FOR CANCER |
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