SUBSTITUTED TRICYCLIC COMPOUNDS WITH ACTIVITY TOWARDS EP1 RECEPTORS

The present invention belongs to the field of EP1 receptor ligands. More specifically it refers to compounds of general formula (I) having great affinity and selectivity for the EP1 receptor. The invention also refers to the process for their preparation, to their use as medicament for the treatment...

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Bibliographic Details
Main Authors FERNANDEZ, JOAN, CARLES, TERRICABRAS, EMMA, AGUILAR, NURIA, SALAS SOLANA, JORDI, CARCELLER GONZALEZ, ELENA
Format Patent
LanguageEnglish
French
Published 10.10.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention belongs to the field of EP1 receptor ligands. More specifically it refers to compounds of general formula (I) having great affinity and selectivity for the EP1 receptor. The invention also refers to the process for their preparation, to their use as medicament for the treatment and/or prophylaxis of diseases or disorders mediated by the EP1 receptor as well as to pharmaceutical compositions comprising them. La présente invention appartient au domaine des ligands des récepteurs EP1. De manière plus spécifique, elle concerne des composés de formule générale (I) présentant une grande affinité et une grande sélectivité pour le récepteur EP1. L'invention concerne également leur procédé de préparation, leur utilisation en tant que médicament pour le traitement et/ou la prophylaxie de maladies ou de troubles médiés par le récepteur EP1 ainsi que des compositions pharmaceutiques les contenant.
Bibliography:Application Number: WO2013EP56886