DNA-DAMAGING AGENT

The problem to be solved by the present invention is to provide a therapeutic agent and a pharmaceutical composition both for diseases associated with the damaging of DNA, particularly solid cancer. The present invention provides a DNA-damaging agent comprising 1-[2'-deoxy-4'-thio-1-beta-D...

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Bibliographic Details
Main Authors NOMURA, MAKOTO, KAZUNO, HIROMI
Format Patent
LanguageEnglish
French
Japanese
Published 12.09.2013
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The problem to be solved by the present invention is to provide a therapeutic agent and a pharmaceutical composition both for diseases associated with the damaging of DNA, particularly solid cancer. The present invention provides a DNA-damaging agent comprising 1-[2'-deoxy-4'-thio-1-beta-D-ribofuranosyl]-5-fluorouracil or a salt thereof as an active ingredient. Le problème à résoudre par la présente invention est de fournir un agent thérapeutique et une composition pharmaceutique destinés tous deux à des maladies associées à des dommages de l'ADN, en particulier un cancer solide. La présente invention concerne ainsi un agent endommageant l'ADN comprenant la 1-[2'-désoxy-4'-thio-1-beta-D-ribofuranosyl]-5-fluorouracile ou son sel comme principe actif.
Bibliography:Application Number: WO2013JP56395