A PROCESS FOR PREPARING PURE CITICOLINE (CDP-CHOLINE)

Disclosed herein is a process for preparing highly pure Citicoline (CDP-Choline) or sodium salt of Citicoline with the aid of dicarboxylic acid or its salts. The process of the present invention results in Citicoline with a purity of more than 99% measured by HPLC. L'invention concerne un procé...

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Bibliographic Details
Main Authors KUMAR, RAJIV, TAMBE, VIJAY, WAGH, ATUL, DHAKE, VILAS, CHAUHAN, YOGENDRA
Format Patent
LanguageEnglish
French
Published 06.09.2013
Subjects
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Summary:Disclosed herein is a process for preparing highly pure Citicoline (CDP-Choline) or sodium salt of Citicoline with the aid of dicarboxylic acid or its salts. The process of the present invention results in Citicoline with a purity of more than 99% measured by HPLC. L'invention concerne un procédé de préparation de Citicoline (CDP-Choline) à pureté élevée ou d'un sel de sodium de Citicoline à l'aide d'un acide dicarboxylique ou de ses sels. Le procédé de la présente invention conduit à une Citicoline ayant une pureté supérieure à 99 % mesurée par HPLC.
Bibliography:Application Number: WO2013IB51585