HEPATITIS C VIRUS INHIBITORS

• Main Authors: FRIDELL, ROBERT, A, TU, YONG, WANG, ALAN XIANGDONG, MEANWELL, NICHOLAS, A, BELEMA, MAKONEN, LOPEZ, OMAR, D, XU, NINGNING, GAO, MIN, KADOW, JOHN, F, SUN, JIN-HUA, GUPTA, SAMAYAMUNTHULA, VENKATA, SATYA, ARUN, KUMAR, HEWAWASAM, PIYASENA, LEMM, JULIE, A, SRINIVASU, POTHUKANURI, O'BOYLE II, DONALD, R, WANG, YING-KAI, WANG, CHUNFU, KUMAR, PONUGUPATI SURESH, KUMAR, INDASI, GOPI
• Format: Patent
• Language: English; French
• Published: 18.07.2013
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein. La présente invention concerne de manière générale des composés antiviraux et, plus spécifiquement, des combinaisons de composés pouvant inhiber la fonction de la protéine NS5A codée par le virus de l'hépatite C (VHC), des compositions comprenant de telles combinaisons et des procédés d'inhibition de la fonction de la protéine NS5A.