PRODUCTION METHOD FOR ORGANIC ACID USING CoA-TRANSFERASE
The present invention relates to a method for producing organic acids by biochemically synthesizing organic acid-CoA using acetyl-CoA as a substrate, and subjecting the organic acid-CoA to a CoA elimination reation by means of a CoA-transferase in the presence of acetic acid, wherein a transformed m...
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Main Authors | , , |
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Format | Patent |
Language | English French Japanese |
Published |
25.04.2013
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to a method for producing organic acids by biochemically synthesizing organic acid-CoA using acetyl-CoA as a substrate, and subjecting the organic acid-CoA to a CoA elimination reation by means of a CoA-transferase in the presence of acetic acid, wherein a transformed microorganism having an enzyme gene cluster for the synthesis of organic acid-CoA using acetyl-CoA as a substrate and a CoA-transferase gene is cultivated to obtain an organic acid.
La présente invention concerne un procédé de production d'acides organiques par la synthèse biochimique d'acide-Coa organique à l'aide d'acétyl-CoA comme substrat, et la soumission de l'acide-CoA organique a une réaction d'élimination de CoA au moyen d'une CoA-transférase en présence d'acide acétique, un microorganisme transformé ayant un groupe de gènes enzymatiques pour la synthèse d'acide-CoA organique à l'aide d'acétyl-CoA comme substrat et un gène CoA-transférase est mis en culture pour obtenir un acide organique. |
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Bibliography: | Application Number: WO2012JP76194 |