ARYLSUBSTITUTED THIAZOLOTRIAZOLES AND THIAZOLOIMIDAZOLES

This disclosure relates to compounds, compositions and methods for the treatment of various disorders. In particular, the disclosure relates to thiazolotriazole and thiazoloimidazole compounds which agonize the activity of the protein TGR5. Formula (I) L'invention concerne des composés, des com...

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Bibliographic Details
Main Authors JIANG, RONG, VEAL, JAMES, M, FITZGERALD, MARK, E, SMITH, EMILIE, D, ATKINSON, ROBERT, N, HUANG, KENNETH, H
Format Patent
LanguageEnglish
French
Published 04.04.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This disclosure relates to compounds, compositions and methods for the treatment of various disorders. In particular, the disclosure relates to thiazolotriazole and thiazoloimidazole compounds which agonize the activity of the protein TGR5. Formula (I) L'invention concerne des composés, des compositions et des méthodes pour le traitement de divers troubles. En particulier, l'invention concerne des composés de thiazolotriazole et de thiazoloimidazole qui perturbent l'activité de la protéine TGR5.
Bibliography:Application Number: WO2012US57942