MICROORGANISM HAVING CARBON DIOXIDE FIXATION PATHWAY INTRODUCED THEREINTO

[Problem] To provide an acetyl-CoA-producing microorganism, which is capable of efficiently synthesizing acetyl-CoA using carbon dioxide, and a substance production method using the same. [Solution] An acetyl-CoA-producing microorganism which has an acetyl-CoA production cycle, said microorganism be...

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Main Authors MATSUMOTO, YOSHIKO, TAKEBAYASHI, NOZOMI, TAKAHASHI, HITOSHI, JURGEN-LOHMANN, DOMINIK LUKAS, ARAKI, TADASHI, WADA, MITSUFUMI, FUJII, RYOTA, MADHAVAN, ANJALI, AMANO, KOH, MORISHIGE, TAKASHI, SHIRAI, TOMOKAZU, SHIMIZU, HIROSHI, FURUSAWA, CHIKARA, ENDO, AYAKO, HIRASAWA, TAKASHI, HIDESAKI, TOMONORI, CHONG, SU SUN, TATENO, TOSHIHIRO
Format Patent
LanguageEnglish
French
Japanese
Published 07.02.2013
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:[Problem] To provide an acetyl-CoA-producing microorganism, which is capable of efficiently synthesizing acetyl-CoA using carbon dioxide, and a substance production method using the same. [Solution] An acetyl-CoA-producing microorganism which has an acetyl-CoA production cycle, said microorganism being obtained by imparting the activity of at least one kind of enzyme selected from the group consisting of malate thiokinase, malyl-CoA lyase, glyoxylate carboligase, 2-hydroxy-3-oxopropionate reductase and hydroxypyruvate reductase. Cette invention concerne un micro-organisme producteur d'acétyl-CoA, qui est capable de synthétiser efficacement l'acétyl-CoA à l'aide de dioxyde de carbone, et un procédé de production de ladite substance l'utilisant. Elle utilise un micro-organisme producteur d'acétyl-CoA ayant un cycle de production d'acétyl-CoA, ledit micro-organisme étant obtenu par un procédé consistant à conférer audit micro-organisme l'activité d'au moins un type d'enzyme choisi dans le groupe constitué par la malate thiokinase, la malyl-CoA lyase, la glyoxylate carboligase, la 2-hydroxy-3-oxopropionate réductase et l'hydroxypyruvate réductase.
Bibliography:Application Number: WO2012JP69247