PROCESS FOR PREPARATION OF DRONEDARONE USING AMIDE INTERMEDIARY COMPOUND

• Main Authors: HUSZAR, CSABA, CSATARINE NAGY, MARIANNA, DOMBRADY, ZSOLT, FRIESZ, ANTAL
• Format: Patent
• Language: English; French
• Published: 31.01.2013
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention relates to a novel process for preparation of dronedarone of formula (I) and pharmaceutically acceptable salts thereof characterized in that the compound of formula (II) is reduced, and the obtained product is isolated and, if desired, converted into a pharmaceutically acceptable salt...