STANDARD SOLUTION FOR USE IN ANALYSIS OF AMINO ACID IN PLASMA

• Main Authors: SHIMBO KAZUTAKA, YOSHIDA HIROO, HAYAKAWA MASAKO
• Format: Patent
• Language: English; French; Japanese
• Published: 24.01.2013
• Subjects: GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION; TECHNICAL SUBJECTS COVERED BY FORMER USPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TESTING

An external standard solution for use in the analysis of an amino acid in plasma, comprising: (1) one or more amino acids independently selected from the components (A) mentioned below each at a concentration of 0.0007 to 0.49 M; and (2) (i) one or more amino acids independently selected from the components (B) mentioned below each at a concentration of 0.2 to 0.9 time smaller than that of an amino acid that is contained at the lowest concentration among the amino acids independently selected from the components (A), (ii) one or more amino acids independently selected from the components (C) mentioned below each at a concentration of 0.1 to 0.4 time smaller than that of an amino acid that is contained at the lowest concentration among the amino acids independently selected from the components (A), or (iii) one or more amino acids independently selected from the components (D) mentioned below each at a concentration of 0.05 to 0.2 time smaller than that of an amino acid that is contained at the lowest concentration among the amino acids independently selected from the components (A): [the components (A)] valine, glycine, alanine and glutamine; [the components (B)] serine, proline, threonine, taurine, leucine, isoleucine, lysine, histidine, phenylalanine and tyrosine; [the components (C)] asparagine, ornithine, arginine and tryptophan; and [the components (D)] glutamic acid, methionine, citrulline and cystine. L'invention concerne une solution témoin externe pour analyse des acides aminés dans le plasma qui comprend : (1) 0,0007M à 0,49M d'au moins un acide aminé choisi parmi des composants (A); et (2) (i) 0,2 à 0,9 fois la densité de l'acide aminé de plus faible densité parmi les acides aminés choisis parmi les composants (A), d'au moins un acide aminé choisi parmi des composants (B), (ii) 0,1 à 0,4 fois la densité de l'acide aminé de plus faible densité parmi les acides aminés choisis parmi les composants (A), d'au moins un acide aminé choisi parmi des composants (C), ainsi que (iii) 0,05 à 0,2 fois la densité de l'acide aminé de plus faible densité parmi les acides aminés choisis parmi les composants (A), d'au moins un acide aminé choisi parmi des composants (D). Composants (A) : valine, glycine, alanine et glutamine; composants (B) : sérine, proline, thréonine, taurine, leucine, isoleucine, lysine, histidine, phénylalanine et tyrosine; composants (C) : asparagine, ornithine, arginine et tryptophane; composants (D) : acide glutamique, méthionine, citrulline et cystine.