MODIFIED LIPASE AND PROCESS FOR PRODUCTION THEREOF, AND REACTION USING SAID ENZYME
The present invention relates to: a modified lipase which has a higher carbamatation activity than that of a wild type thereof represented by SEQ ID NO: 1 and which is produced by the substitution of a glutamine residue located at position-193 in SEQ ID NO: 1 by another amino acid residue, or a muta...
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Main Authors | , , |
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Format | Patent |
Language | English French Japanese |
Published |
08.11.2012
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to: a modified lipase which has a higher carbamatation activity than that of a wild type thereof represented by SEQ ID NO: 1 and which is produced by the substitution of a glutamine residue located at position-193 in SEQ ID NO: 1 by another amino acid residue, or a mutant of the modified lipase, which is produced by the substitution, deletion, insertion, addition or inversion of one or several amino acid residues in SEQ ID NO: 1; a process for producing a carbamate compound using the modified lipase or the mutant; and a process for producing a carbamate compound using a known modified lipase.
Cette invention concerne : une lipase modifiée ayant une activité de carbamatation supérieure à celle du type sauvage représentée par SEQ ID No.: 1 et qui est obtenue par substitution d'un résidu glutamine qui se trouve à la position 193 de SEQ ID No.: 1 par un autre résidu acide aminé, ou un mutant de ladite lipase modifiée, qui est obtenu par substitution, délétion, insertion, addition ou inversion d'un ou de plusieurs résidus acides aminés de SEQ ID No.: 1 ; un procédé de production d'un composé de carbamate faisant appel à ladite lipase modifiée ou audit mutant ; et un procédé de production d'un composé de carbamate faisant appel à une lipase modifiée connue. |
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Bibliography: | Application Number: WO2012JP61326 |