INHIBITORS OF INDUCIBLE FORM OF 6-PHOSPHOFRUCTOSE-2-KINASE

The invention is directed to inhibitors of inducible form of 6-phosphofructose-2-kinase of formula I, as well as to pharmaceutically acceptable salts of formula I, and pharmaceutical compositions comprising a compound of formula I. The compounds can be used to treat cancer. La présente invention con...

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Main Authors MOON, KIM, KEARNEY, PATRICK, TSUHAKO, AMY, LEW, ZAHARIA, CHRISTIANA, A, BAJJALIEH, WILLIAM, TESFAI, ZEROM, AAY, NAING, MARLOWE, CHARLES, K, HUANG, PING, XU, WEI, KABIGTING, LORI, NUSS, JOHN, M, TAMBO-ONG, ARLYN
Format Patent
LanguageEnglish
French
Published 01.11.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention is directed to inhibitors of inducible form of 6-phosphofructose-2-kinase of formula I, as well as to pharmaceutically acceptable salts of formula I, and pharmaceutical compositions comprising a compound of formula I. The compounds can be used to treat cancer. La présente invention concerne des inhibiteurs de la forme inductible de la 6-phosphofructose-2-kinase de formule (I), ainsi que les sels pharmaceutiquement acceptables de formule (I), et des compositions pharmaceutiques comprenant un composé de formule (I). Les composés peuvent servir à traiter le cancer.
Bibliography:Application Number: WO2012US35794