POLYMER CONJUGATES TARGETING CELLS AND METHODS RELATED THERETO

This disclosure relates to polymer coated particles targeting cancer cells and methods related thereto. In certain embodiments, the disclosure relates to nanoparticles coated with amphiphilic polymers conjugated with molecules useful for targeting tumors, monitoring the location of the nanoparticles...

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Bibliographic Details
Main Authors YANG, LILY, MAO, HUI, LIPOWSKA, MALGORZATA, LEE, GEE YOUNG
Format Patent
LanguageEnglish
French
Published 31.01.2013
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This disclosure relates to polymer coated particles targeting cancer cells and methods related thereto. In certain embodiments, the disclosure relates to nanoparticles coated with amphiphilic polymers conjugated with molecules useful for targeting tumors, monitoring the location of the nanoparticles administered to a subject by MRI, and viewing the presence of the nanoparticles during optical image-guided surgery. L'invention porte sur des cellules cancéreuses de ciblage de particules enrobées de polymère et sur ses procédés associés. Dans certains modes de réalisation, l'invention porte sur des nanoparticules enrobées de polymères amphiphiles conjugués à des molécules utiles pour le ciblage de tumeurs, la surveillance de l'emplacement des nanoparticules administrées à un sujet par imagerie par résonance magnétique (IRM), et la visualisation de la présence des nanoparticules durant une chirurgie guidée par image optique.
Bibliography:Application Number: WO2012US31341