PEGYLATED APELIN AND USES THEREOF

The invention provides compositions and methods for treating a disease or disorder associated with Apelin. Specifically, the invention relates to a pegylated form of Apelin to provide extended circulating life and inotropic effects, and thereby efficiently treat diseases or disorders associated with...

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Bibliographic Details
Main Authors JIA, Zhiqiang, PAN, Clark Q, HOU, Lihui, AKITA, Geoffrey Y
Format Patent
LanguageEnglish
French
Published 25.01.2018
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention provides compositions and methods for treating a disease or disorder associated with Apelin. Specifically, the invention relates to a pegylated form of Apelin to provide extended circulating life and inotropic effects, and thereby efficiently treat diseases or disorders associated with Apelin. L'invention concerne des compositions et des méthodes de traitement d'une maladie ou d'un trouble associé à l'apeline. Plus particulièrement, l'invention concerne une forme pégylée de l'apeline, ce qui lui permet une vie dans la circulation et des effets inotropes prolongés, ainsi que de traiter efficacement des maladies ou des troubles associés à l'apeline.
Bibliography:Application Number: WO2012US28298