METHOD FOR PRODUCING TARGET SUBSTANCE BY FERMENTATION PROCESS

A method for efficiently producing a target substance, said method comprising: culturing in a medium a coryneform bacterium, which has lowered or no activity, compared with a parent strain, of a PTS protein relating to fructose uptake and is capable of producing the target substance; thus producing...

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Bibliographic Details
Main Authors UJIHARA, TETSURO, YAGASAKI, MAKOTO, ABE, TETSUYA
Format Patent
LanguageEnglish
French
Japanese
Published 16.08.2012
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:A method for efficiently producing a target substance, said method comprising: culturing in a medium a coryneform bacterium, which has lowered or no activity, compared with a parent strain, of a PTS protein relating to fructose uptake and is capable of producing the target substance; thus producing and accumulating the target substance in the culture medium; and then harvesting the target substance from the culture medium. Cette invention concerne un procédé permettant de produire efficacement une substance cible et consistant à : mettre en culture dans un milieu une bactérie corynéforme, dont l'activité est réduite ou nulle par rapport à une souche parent, une protéine du système PTS associée à l'absorption du fructose et capable de produire la substance cible ; produire ainsi et accumuler la substance cible dans le milieu de culture ; et récolter la substance cible dans le milieu de culture.
Bibliography:Application Number: WO2012JP52947