METHOD AND APPARATUS FOR IN VIVO OPTICAL MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION

• Main Authors: CHERNOBROD, BORIS, M, SCHWARTZ, VLADIMIR
• Format: Patent
• Language: English; French
• Published: 20.03.2014
• Subjects: DIAGNOSIS; HUMAN NECESSITIES; HYGIENE; IDENTIFICATION; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEDICAL OR VETERINARY SCIENCE; PHYSICS; SURGERY; TESTING

A method of non-invasive measurement of the glucose concentration directly in the blood flow utilizes a combination of the differential scattering spectroscopy and confocal scanning laser Doppler microscopy. In order to distinguish between the light scattering in tissues in blood, a method of confocal scanning Doppler microscopy (CSDM) is applied. In this method, two coaxial laser beams are focused inside of the blood vessels. The backscattenng beams are separated by the dispersion element and the backscattenng signal includes a frequency shifted optical signal due to the scattering from moving RBC and a non-shifted optical signal due to scattering from skin static structures. La présente invention concerne un procédé de mesure non invasive de la glycémie, directement dans le courant sanguin. Le procédé fait appel à la spectroscopie de diffusion différentielle et à la microscopie confocale à balayage laser à effet Doppler.