METABOTROPIC GLUTAMATE RECEPTOR MODULATORS

The invention relates to heterocyclic derivatives as well as their pharmaceutically acceptable salts. The invention further relates to a process for the preparation of such compounds. The compounds of the invention are mGluR5 modulators and are therefore useful for the control and prevention of acut...

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Bibliographic Details
Main Authors KUBAS, HOLGER, MEYER, UDO, KRUEGER, BJOERN, ZEMRIBO, RONALDS, ABEL, ULRICH
Format Patent
LanguageEnglish
French
Published 28.06.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to heterocyclic derivatives as well as their pharmaceutically acceptable salts. The invention further relates to a process for the preparation of such compounds. The compounds of the invention are mGluR5 modulators and are therefore useful for the control and prevention of acute and/or chronic neurological disorders. La présente invention concerne des dérivés hétérocycliques ainsi que leurs sels de qualité pharmaceutique. La présente invention concerne en outre un procédé de synthèse de tels composés. Les composés selon l'invention sont des modulateurs de mGluR5 et peuvent donc être employés dans la régulation et la prévention des troubles neurologiques aigus et/ou chroniques.
Bibliography:Application Number: WO2011EP73711