ANTIBACTERIAL AMIINOGLYCOSIDE ANALOGS

Compounds having antibacterial activity are disclosed. The compounds have a structure including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein Q1 and Q2 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical com...

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Main Authors HILDEBRANDT, DARIN JAMES, LINSELL, MARTIN SHERINGHAM, GOLDBLUM, ADAM AARON, KANE, TIMOTHY ROBERT, AGGEN, JAMES BRADLEY, GLIEDT, MICAH JAMES, DOZZO, PAOLA
Format Patent
LanguageEnglish
French
Published 24.05.2012
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Summary:Compounds having antibacterial activity are disclosed. The compounds have a structure including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein Q1 and Q2 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed. Composés ayant une activité antibactérienne. Les composés selon l'invention ont une structure comprenant les stéréoisomères, les promédicaments et leurs sels de qualité pharmaceutique, Q1 et Q2 étant tels que définis dans la description. Des procédés associés à la préparation et à l'utilisation de ces composés, ainsi que des compositions pharmaceutiques les contenant sont également décrits.
Bibliography:Application Number: WO2011US60513