PIPERAZINYLPYRIMIDINE ANALOGUES AS PROTEIN KINASE INHIBITORS

The invention provides novel compounds based on piperazinylpyrimidine derivatives to be used as protein kinase inhibitors. The compounds may be useful in treating or preventing different cellular proliferation disorders, such as cancer. The present invention also provides methods of preparing these...

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Bibliographic Details
Main Authors SHALLAL, HASSAN, M, RUSSU, WADE, A
Format Patent
LanguageEnglish
French
Published 01.03.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention provides novel compounds based on piperazinylpyrimidine derivatives to be used as protein kinase inhibitors. The compounds may be useful in treating or preventing different cellular proliferation disorders, such as cancer. The present invention also provides methods of preparing these compounds, and methods of using the same. L'invention concerne de nouveaux composés à base de dérivés de pipérazinylpyrimidine à utiliser en tant qu'inhibiteurs de protéine kinase. Les composés peuvent être utiles dans le traitement ou la prévention de différents troubles de prolifération cellulaire, tels que le cancer. La présente invention concerne en outre des procédés de préparation de ces composés, et des procédés d'utilisation de ceux-ci.
Bibliography:Application Number: WO2011US48999