STABILIZED OPHTHALMIC GALACTOMANNAN FORMULATIONS

The present invention relates to viscosity stabilized ophthalmic formulations and ophthalmic formulations suitable for drug delivery. The formulations comprise galactomannans such as guar or hydroxypropyl guar and a borate source such as boric acid. The formulations further comprise a diol alcohol s...

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Bibliographic Details
Main Authors KETELSON, HOWARD, ALLEN, DAVIS, JAMES, W, MEADOWS, DAVID, L
Format Patent
LanguageEnglish
French
Published 10.11.2011
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to viscosity stabilized ophthalmic formulations and ophthalmic formulations suitable for drug delivery. The formulations comprise galactomannans such as guar or hydroxypropyl guar and a borate source such as boric acid. The formulations further comprise a diol alcohol such as sorbitol and, optionally, a pharmaceutically acceptable divalent cation salt such as magnesium chloride. La présente invention concerne des formulations ophtalmiques à viscosité stabilisée et des formulations ophtalmiques adaptées pour l'administration de médicament. Les formulations comprennent des galactomannanes tels que le guar ou l'hydroxypropyl-guar et une source de borate telle que l'acide borique. Les formulations comprennent en outre un alcool diol tel que le sorbitol et, facultativement, un sel de cation divalent pharmaceutiquement acceptable tel que le chlorure de magnésium.
Bibliography:Application Number: WO2011US35165