INDOLIZINE AND IMIDAZOPYRIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS

The invention relates to compounds of formula (I) wherein A, R1 to R8 have the meaning as cited in the description and the claims. Said compounds are useful as Orexin Receptor antagonists. The invention also relates to pharmaceutical compositions, the preparation of such compounds as well as the pro...

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Bibliographic Details
Main Authors DAVENPORT, TARA, BENTLEY, JONATHAN, MARK, HALLETT, DAVID, JAMES
Format Patent
LanguageEnglish
French
Published 10.11.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to compounds of formula (I) wherein A, R1 to R8 have the meaning as cited in the description and the claims. Said compounds are useful as Orexin Receptor antagonists. The invention also relates to pharmaceutical compositions, the preparation of such compounds as well as the production and use as medicament. L'invention concerne des composés de formule (I) dans laquelle la signification de A, R1 à R8 est telle qu'elle apparaît dans le descriptif et les revendications. Lesdits composés sont utilisés comme antagonistes de récepteurs d'orexine. L'invention concerne également des compositions pharmaceutiques, leur préparation ainsi que leur production et utilisation comme médicament.
Bibliography:Application Number: WO2011EP56939