METHODS FOR IMPROVING SPERM FUNCTIONALITY

• Main Authors: DICKER, BRIDGET LEE, DE GREGORIO, FRANCESCA, JAYASINGHE, SHAKEELA NATHALIA, HONG, JIWON, HUDSON, KEITH
• Format: Patent
• Language: English; French
• Published: 09.09.2011
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BEER; BIOCHEMISTRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMES; ENZYMOLOGY; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PEST REPELLANTS OR ATTRACTANTS; PHYSICS; PLANT GROWTH REGULATORS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; TESTING; TRAPPING; VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS; VINEGAR; WINE

Methods for improving the functionality and/or fertility of sperm, for example, by enhancing motility and extending the lifespan of sperm in the female reproductive tract, are provided, such methods comprising contacting semen and/or sperm with an effective amount of a composition comprising a mitochondria targeted antioxidant. L'invention concerne des procédés visant améliorer la fonctionnalité et/ou la fertilité du sperme, par exemple, par le renforcement de la motilité et l'allongement de la durée de vie du sperme dans l'appareil génital féminin, ces procédés comprenant la mise en contact de sperme avec une quantité efficace d'une composition comprenant un antioxydant ciblé sur les mitochondries.