INHIBITORS OF HEPATITIS C VIRUS NS5B POLYMERASE

Disclosed are compounds of formula (I) that are used as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication a...

Full description

Saved in:
Bibliographic Details
Main Authors SOLL, RICHARD, WU, HAO, KOCH, UWE, MCCOMAS, CASEY, CAMERON, LIVERTON, NIGEL, J, PENG, XUANJIA, LI, PENG, NARJES, FRANK, HABERMANN, JOERG, LIU, SHILAN
Format Patent
LanguageEnglish
French
Published 09.09.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:Disclosed are compounds of formula (I) that are used as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and /or viral production in a cell-based system. La présente invention concerne des composés de formule (I) qui sont utilisés en tant qu'inhibiteurs de polymérase du virus de l'hépatite C (VHC) NS5B, la synthèse de ces composés, et l'utilisation de ces composés pour inhiber l'activité polymérase VHC NS5B, pour traiter ou prévenir l'infection par le VHC et pour inhiber la réplication virale du VHC et/ou la production virale dans un système à base de cellules.
Bibliography:Application Number: WO2011CN00332