RESPIRATORY VIRUS EPITOPES TEMPLATED INTO DOUBLE STRANDED COILED -COILS AND USE THEREOF IN IMMUNIZATION

Templated conjugates created from naturally- occurring protein sequences found in pathogens, such as viruses, are disclosed. The sequences are "templated" into a consensus coiled-coil sequence in order to form a two- stranded antigen suitable for immunization of a subject. L'invention...

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Main Authors YAN, ZHE, HARTSOCK, WENDY, J, HODGES, ROBERT, S, QIAN, ZHAOHUI, HIRSCH, BROOKE, ELIZABETH BISHOP, HOLMES, KATHRYN, V
Format Patent
LanguageEnglish
French
Published 19.04.2012
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Templated conjugates created from naturally- occurring protein sequences found in pathogens, such as viruses, are disclosed. The sequences are "templated" into a consensus coiled-coil sequence in order to form a two- stranded antigen suitable for immunization of a subject. L'invention concerne des conjugués à matrice créés à partir de séquences protéiques d'origine naturelle trouvées chez des organismes pathogènes, tels que des virus. Les séquences sont mises en « matrice » dans une séquence consensus en superhélice afin de former un antigène double brin approprié à l'immunisation d'un sujet.
Bibliography:Application Number: WO2011US22639