PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS
The present invention provides Pyrazolopyrimidine Compounds of Formula (I): (I) wherein L, T, Z, U, V, W, R3, R6, R7, R8, and m are as defined herein, and pharmaceutically acceptable salts of such Pyrazolopyrimidine Compounds. The Pyrazolopyrimidine Compounds are useful in the treatment of cancer an...
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Main Authors | , , , , , , , , , , , , , , , , , |
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Format | Patent |
Language | English French |
Published |
28.07.2011
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention provides Pyrazolopyrimidine Compounds of Formula (I): (I) wherein L, T, Z, U, V, W, R3, R6, R7, R8, and m are as defined herein, and pharmaceutically acceptable salts of such Pyrazolopyrimidine Compounds. The Pyrazolopyrimidine Compounds are useful in the treatment of cancer and other diseases or disorders wherein mTOR is deregulated.
La présente invention porte sur des composés pyrazolopyrimidines de Formule (I) : (I), dans laquelle L, T, Z, U, V, W, R3, R6, R7, R8 et m sont tels que définis dans l'invention, et sur des sels pharmaceutiquement acceptables de ces composés pyrazolopyrimidines. Les composés pyrazolopyrimidines sont utiles dans le traitement du cancer et autres maladies ou troubles dans lesquels il y a une dérégulation du mTOR. |
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Bibliography: | Application Number: WO2011US21534 |